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testosterone

a major sex hormone produced by the human body, that affect male appearance and sexual development in profound ways, such as those that develop during puberty.

With transgender and gender non conforming individuals, puberty blockers may be prescribed to prevent the related changes in puberty caused by testosterone in those assigned male at birth. Feminising Hormone Therapy will reduce the level of testosterone whilst providing estrogen; Masculinising Hormone Therapy will increase the level of testosterone.